Glycine + NAC (GlyNAC) vs Shilajit (Purified)

Side-by-side comparison of mechanisms, dosing, interactions, and stacking potential.

Glycine + NAC (GlyNAC)Shilajit (Purified)
CategorySupplementsSupplements
Standard Dose
Timing
Cycle Duration
Evidence LevelStrongModerate

Mechanism

Combination that restores glutathione synthesis. Age-related glutathione deficiency is driven by glycine and cysteine precursor depletion, not enzyme dysfunction. GlyNAC corrects oxidative stress, mitochondrial dysfunction, inflammation, and insulin resistance in older adults.

Contraindications

  • Active stomach ulcer (NAC)
  • Asthma (NAC may cause bronchospasm in rare cases)

Mechanism

Fulvic acid-rich mineral complex that enhances mitochondrial CoQ10 function, increases testosterone (via FSH), and acts as a potent electron carrier in the ETC. Enhances bioavailability of other supplements. Contains dibenzo-alpha-pyrones and fulvic acids.

Contraindications

  • Hemochromatosis
  • Must use purified form — raw shilajit may contain heavy metals

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