Apigenin vs Shilajit (Purified)

Side-by-side comparison of mechanisms, dosing, interactions, and stacking potential.

ApigeninShilajit (Purified)
CategorySupplementsSupplements
Standard Dose
Timing
Cycle Duration
Evidence LevelModerateModerate
A

Apigenin

Supplements

Mechanism

Flavonoid (found in chamomile, parsley) that inhibits CD38, the primary NAD+-consuming enzyme. Also a potent aromatase inhibitor and anxiolytic via GABA-A modulation. Supports NAD+ levels, reduces estrogen conversion, and improves sleep quality.

Contraindications

  • Caution in pregnancy (uterotonic potential at high doses)

Mechanism

Fulvic acid-rich mineral complex that enhances mitochondrial CoQ10 function, increases testosterone (via FSH), and acts as a potent electron carrier in the ETC. Enhances bioavailability of other supplements. Contains dibenzo-alpha-pyrones and fulvic acids.

Contraindications

  • Hemochromatosis
  • Must use purified form — raw shilajit may contain heavy metals

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