Side-by-side comparison of mechanisms, dosing, interactions, and stacking potential.
| Fadogia Agrestis | Shilajit | |
|---|---|---|
| Category | Adaptogens | Adaptogens |
| Standard Dose | 400-600mg daily | 250-500mg purified shilajit daily (standardized to >50% fulvic acid) |
| Timing | Morning with food. | Morning with warm water or milk (traditional Ayurvedic method). Can be split AM/PM. |
| Cycle Duration | Cycle 4-8 weeks on, 2-4 weeks off (limited long-term safety data) | Cycle 8-12 weeks on, 2-4 weeks off |
| Evidence Level | animal_plus_anecdotal | moderate_human |
Fadogia agrestis stem extract contains saponins and alkaloids that appear to increase luteinizing hormone (LH) release from the anterior pituitary, stimulating Leydig cell testosterone production. Animal studies suggest it may also have direct effects on testicular steroidogenic enzymes and may increase testicular weight. The saponin content may modulate gonadotropin-releasing hormone (GnRH) pulse frequency. The aphrodisiac effects are likely mediated through increased testosterone and possibly direct effects on dopaminergic and nitrergic pathways.
400-600mg daily
Morning with food.
Cycle 4-8 weeks on, 2-4 weeks off (limited long-term safety data)
Shilajit is a mineral-rich exudate containing fulvic acid (60-80%), dibenzo-alpha-pyrones (DBPs), and over 85 minerals in ionic form. Fulvic acid acts as an electron shuttle in mitochondrial electron transport, enhancing CoQ10 function and ATP production. DBPs protect CoQ10 from oxidation, extending its functional half-life. Shilajit increases total and free testosterone by stimulating steroidogenesis and reducing SHBG. It also enhances mitochondrial membrane potential, acts as a potent antioxidant (fulvic acid neutralizes free radicals), and improves mineral absorption by forming bioavailable fulvic acid-mineral complexes.
250-500mg purified shilajit daily (standardized to >50% fulvic acid)
Morning with warm water or milk (traditional Ayurvedic method). Can be split AM/PM.
Cycle 8-12 weeks on, 2-4 weeks off
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