Side-by-side comparison of mechanisms, dosing, interactions, and stacking potential.
| Astragalus (Astragalus membranaceus) | Fadogia Agrestis | |
|---|---|---|
| Category | Adaptogens | Adaptogens |
| Standard Dose | — | 400-600mg daily |
| Timing | — | Morning with food. |
| Cycle Duration | — | Cycle 4-8 weeks on, 2-4 weeks off (limited long-term safety data) |
| Evidence Level | Moderate | animal_plus_anecdotal |
Contains cycloastragenol and astragaloside IV which activate telomerase (hTERT). Adaptogenic — modulates immune function, reduces inflammation, and supports cardiovascular health. Used in traditional Chinese medicine for Qi tonification.
Fadogia agrestis stem extract contains saponins and alkaloids that appear to increase luteinizing hormone (LH) release from the anterior pituitary, stimulating Leydig cell testosterone production. Animal studies suggest it may also have direct effects on testicular steroidogenic enzymes and may increase testicular weight. The saponin content may modulate gonadotropin-releasing hormone (GnRH) pulse frequency. The aphrodisiac effects are likely mediated through increased testosterone and possibly direct effects on dopaminergic and nitrergic pathways.
400-600mg daily
Morning with food.
Cycle 4-8 weeks on, 2-4 weeks off (limited long-term safety data)
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