Side-by-side comparison of mechanisms, dosing, interactions, and stacking potential.
| Cordyceps Militaris | Shilajit | |
|---|---|---|
| Category | Adaptogens | Adaptogens |
| Standard Dose | 1000-3000mg daily (fruiting body extract) or 500-1000mg (concentrated 10:1 extract) | 250-500mg purified shilajit daily (standardized to >50% fulvic acid) |
| Timing | Morning or pre-workout (energizing). Avoid evening dosing. | Morning with warm water or milk (traditional Ayurvedic method). Can be split AM/PM. |
| Cycle Duration | Cycle 8-12 weeks on, 2 weeks off, or continuous | Cycle 8-12 weeks on, 2-4 weeks off |
| Evidence Level | moderate_human | moderate_human |
Cordyceps contains cordycepin (3'-deoxyadenosine) and adenosine, which modulate purinergic signaling. Cordycepin activates AMPK, inhibits mTOR, and modulates adenosine receptors (A1, A2A, A3). It enhances cellular ATP production by upregulating mitochondrial biogenesis genes and improving oxygen utilization efficiency. Cordyceps increases EPO production (erythropoietin) via HIF-1alpha stabilization, enhancing oxygen-carrying capacity. Beta-glucans (1,3/1,6) activate innate immune cells via Dectin-1 and complement receptor 3 (CR3). It also relaxes bronchial smooth muscle and enhances adrenal hormone production.
1000-3000mg daily (fruiting body extract) or 500-1000mg (concentrated 10:1 extract)
Morning or pre-workout (energizing). Avoid evening dosing.
Cycle 8-12 weeks on, 2 weeks off, or continuous
Shilajit is a mineral-rich exudate containing fulvic acid (60-80%), dibenzo-alpha-pyrones (DBPs), and over 85 minerals in ionic form. Fulvic acid acts as an electron shuttle in mitochondrial electron transport, enhancing CoQ10 function and ATP production. DBPs protect CoQ10 from oxidation, extending its functional half-life. Shilajit increases total and free testosterone by stimulating steroidogenesis and reducing SHBG. It also enhances mitochondrial membrane potential, acts as a potent antioxidant (fulvic acid neutralizes free radicals), and improves mineral absorption by forming bioavailable fulvic acid-mineral complexes.
250-500mg purified shilajit daily (standardized to >50% fulvic acid)
Morning with warm water or milk (traditional Ayurvedic method). Can be split AM/PM.
Cycle 8-12 weeks on, 2-4 weeks off
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