Side-by-side comparison of mechanisms, dosing, interactions, and stacking potential.
| Bromelain | Sulforaphane (from Broccoli Sprout Extract) | |
|---|---|---|
| Category | Supplements | Supplements |
| Standard Dose | — | — |
| Timing | — | — |
| Cycle Duration | — | — |
| Evidence Level | Moderate | Strong |
Proteolytic enzyme complex from pineapple stems. Anti-inflammatory via modulation of prostaglandin synthesis, fibrinolytic, and anti-edematous. Degrades fibrin and reduces blood viscosity. Enhances absorption of other supplements (particularly quercetin and curcumin).
Isothiocyanate that activates Nrf2 — the master regulator of antioxidant defense. Upregulates glutathione synthesis, phase II detoxification enzymes, and heat shock proteins. Also inhibits HDAC (epigenetic modifier) and NF-kB (anti-inflammatory).
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