Isothiocyanate that activates Nrf2 — the master regulator of antioxidant defense. Upregulates glutathione synthesis, phase II detoxification enzymes, and heat shock proteins. Also inhibits HDAC (epigenetic modifier) and NF-kB (anti-inflammatory).
Interactions
May reduce effectiveness of CYP1A2 substrates (caffeine)
Synergistic with curcumin for NF-kB inhibition
Contraindications
Thyroid conditions (goitrogen at very high doses)
Cruciferous vegetable allergy
Key Papers
Fahey et al. 2017 - Broccoli sprouts and sulforaphane in clinical trials (Molecular Nutrition & Food Research)
Disclaimer: This information is for educational purposes only and is not medical advice. BioAccelera Labs does not diagnose, treat, or prescribe. Consult a licensed healthcare provider before using any compound.
Should Sulforaphane (from Broccoli Sprout Extract) Be in Your Stack?
Take the free assessment and get personalized recommendations based on your biology and goals.