Bromelain vs Pterostilbene

Side-by-side comparison of mechanisms, dosing, interactions, and stacking potential.

BromelainPterostilbene
CategorySupplementsSupplements
Standard Dose
Timing
Cycle Duration
Evidence LevelModerateModerate
A

Bromelain

Supplements

Mechanism

Proteolytic enzyme complex from pineapple stems. Anti-inflammatory via modulation of prostaglandin synthesis, fibrinolytic, and anti-edematous. Degrades fibrin and reduces blood viscosity. Enhances absorption of other supplements (particularly quercetin and curcumin).

Contraindications

  • Pineapple allergy
  • Pre-surgery (bleeding risk)
  • Active bleeding
B

Pterostilbene

Supplements

Mechanism

Dimethylated analog of resveratrol with 4x greater oral bioavailability. Activates SIRT1 and AMPK, reduces oxidative stress, and improves lipid profiles. Superior pharmacokinetics compared to resveratrol due to methyl groups protecting against glucuronidation.

Contraindications

  • Hormone-sensitive conditions (mild estrogenic activity)

Not sure which is right for you?

Take our free assessment to get personalized recommendations based on your health goals, current stack, and biomarkers.

Get Your Free Protocol →or take the assessment →