Supplements

Pterostilbene

Evidence: Moderate

Mechanism of Action

Dimethylated analog of resveratrol with 4x greater oral bioavailability. Activates SIRT1 and AMPK, reduces oxidative stress, and improves lipid profiles. Superior pharmacokinetics compared to resveratrol due to methyl groups protecting against glucuronidation.

Interactions

  • May potentiate anticoagulants
  • CYP1A2 inducer

Contraindications

  • Hormone-sensitive conditions (mild estrogenic activity)

Key Papers

  • Riche et al. 2014 - Pterostilbene lowers cholesterol (Journal of Clinical Pharmacology)
Disclaimer: This information is for educational purposes only and is not medical advice. BioAccelera Labs does not diagnose, treat, or prescribe. Consult a licensed healthcare provider before using any compound.

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