Side-by-side comparison of mechanisms, dosing, interactions, and stacking potential.
| AOD-9604 | Epitalon | |
|---|---|---|
| Category | Growth Factors | Growth Factors |
| Standard Dose | Research indicates 250-300 mcg daily via subcutaneous injection, administered in the morning on an empty stomach. | — |
| Timing | Morning administration on empty stomach, at least 30 minutes before eating. Fasted state enhances lipolytic effect. | — |
| Cycle Duration | 12-20 week cycles. | — |
| Evidence Level | moderate_human | Emerging |
AOD-9604 is a synthetic 16-amino acid fragment (residues 176-191) of the C-terminal domain of human growth hormone with a tyrosine substitution at the N-terminus. It selectively stimulates lipolysis by upregulating beta-3 adrenergic receptors in adipose tissue while inhibiting lipogenesis. It modulates lipid and glucose metabolism through beta-adrenergic and AMPK-related pathways without influencing IGF-1 activity, growth, or insulin sensitivity — retaining GH's fat-burning properties without its growth-promoting effects.
Research indicates 250-300 mcg daily via subcutaneous injection, administered in the morning on an empty stomach.
Morning administration on empty stomach, at least 30 minutes before eating. Fasted state enhances lipolytic effect.
12-20 week cycles.
Synthetic tetrapeptide studied in Russian longevity literature for pineal signaling, circadian regulation, and telomerase-related hypotheses.
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