Pentadecanoic Acid (C15:0 / Fatty15) vs Urolithin A

Side-by-side comparison of mechanisms, dosing, interactions, and stacking potential.

Pentadecanoic Acid (C15:0 / Fatty15)Urolithin A
CategorySupplementsSupplements
Standard Dose
Timing
Cycle Duration
Evidence LevelEmergingModerate-Strong

Mechanism

Odd-chain saturated fatty acid identified as essential. Strengthens cell membranes by integrating into phospholipid bilayer, activates AMPK and PPAR-alpha/delta, and inhibits mTOR. Repairs mitochondrial function. Epidemiologically associated with reduced cardiometabolic disease.

Contraindications

  • None established
B

Urolithin A

Supplements

Mechanism

Gut metabolite of ellagitannins that activates mitophagy — selective clearance of damaged mitochondria. Improves mitochondrial function, muscle endurance, and cellular energy production. Only ~40% of population can produce it endogenously.

Contraindications

  • Limited long-term safety data beyond 4 months

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