Glycine + NAC (GlyNAC) vs Wobenzym (Systemic Enzyme Complex)

Side-by-side comparison of mechanisms, dosing, interactions, and stacking potential.

Glycine + NAC (GlyNAC)Wobenzym (Systemic Enzyme Complex)
CategorySupplementsSupplements
Standard Dose
Timing
Cycle Duration
Evidence LevelStrongModerate

Mechanism

Combination that restores glutathione synthesis. Age-related glutathione deficiency is driven by glycine and cysteine precursor depletion, not enzyme dysfunction. GlyNAC corrects oxidative stress, mitochondrial dysfunction, inflammation, and insulin resistance in older adults.

Contraindications

  • Active stomach ulcer (NAC)
  • Asthma (NAC may cause bronchospasm in rare cases)

Mechanism

Combination of bromelain, papain, trypsin, chymotrypsin, and pancreatin. Systemic enzyme therapy that degrades circulating immune complexes, reduces fibrin deposition, modulates cytokines (IL-6, TNF-alpha), and supports recovery from injury, surgery, and chronic inflammation.

Contraindications

  • Bleeding disorders
  • Pre-surgery
  • Severe liver or kidney disease

Not sure which is right for you?

Take our free assessment to get personalized recommendations based on your health goals, current stack, and biomarkers.

Get Your Free Protocol →or take the assessment →