Side-by-side comparison of mechanisms, dosing, interactions, and stacking potential.
| Citrus Bergamot Extract | Pyrroloquinoline Quinone (PQQ) | |
|---|---|---|
| Category | Supplements | Supplements |
| Standard Dose | — | — |
| Timing | — | — |
| Cycle Duration | — | — |
| Evidence Level | Moderate-Strong | Moderate |
Contains brutieridin and melitidin — statin-like HMG-CoA reductase inhibitors from bergamot orange. Activates AMPK, improves lipid profiles (reduces LDL, increases HDL), and has antioxidant effects. Supports cardiovascular and metabolic health.
Redox cofactor that stimulates mitochondrial biogenesis via PGC-1alpha activation. Potent antioxidant (5000x more efficient than vitamin C in redox cycling). Supports nerve growth factor (NGF) synthesis and protects neurons from oxidative damage.
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