Side-by-side comparison of mechanisms, dosing, interactions, and stacking potential.
| Citrus Bergamot Extract | Pycnogenol | |
|---|---|---|
| Category | Supplements | Supplements |
| Standard Dose | — | — |
| Timing | — | — |
| Cycle Duration | — | — |
| Evidence Level | Moderate-Strong | Moderate |
Contains brutieridin and melitidin — statin-like HMG-CoA reductase inhibitors from bergamot orange. Activates AMPK, improves lipid profiles (reduces LDL, increases HDL), and has antioxidant effects. Supports cardiovascular and metabolic health.
Polyphenol-rich French maritime pine bark extract that improves endothelial nitric oxide signaling, capillary tone, and oxidative defense.
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