Citrus Bergamot Extract vs Luteolin

Side-by-side comparison of mechanisms, dosing, interactions, and stacking potential.

Citrus Bergamot ExtractLuteolin
CategorySupplementsSupplements
Standard Dose
Timing
Cycle Duration
Evidence LevelModerate-StrongEmerging

Mechanism

Contains brutieridin and melitidin — statin-like HMG-CoA reductase inhibitors from bergamot orange. Activates AMPK, improves lipid profiles (reduces LDL, increases HDL), and has antioxidant effects. Supports cardiovascular and metabolic health.

Contraindications

  • Rhabdomyolysis risk if combined with high-dose statins without monitoring
B

Luteolin

Supplements

Mechanism

Flavone that modulates mast-cell activation, microglial signaling, and inflammatory cascades including NF-kB activity.

Contraindications

  • Limited pregnancy data

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