Bromelain vs HMB

Side-by-side comparison of mechanisms, dosing, interactions, and stacking potential.

BromelainHMB
CategorySupplementsSupplements
Standard Dose
Timing
Cycle Duration
Evidence LevelModerateModerate
A

Bromelain

Supplements

Mechanism

Proteolytic enzyme complex from pineapple stems. Anti-inflammatory via modulation of prostaglandin synthesis, fibrinolytic, and anti-edematous. Degrades fibrin and reduces blood viscosity. Enhances absorption of other supplements (particularly quercetin and curcumin).

Contraindications

  • Pineapple allergy
  • Pre-surgery (bleeding risk)
  • Active bleeding
B

HMB

Supplements

Mechanism

Leucine metabolite that reduces muscle protein breakdown and may support recovery under high training or caloric deficit conditions.

Contraindications

  • None established at standard doses

Not sure which is right for you?

Take our free assessment to get personalized recommendations based on your health goals, current stack, and biomarkers.

Get Your Free Protocol →or take the assessment →