Black Seed Oil (Nigella sativa) vs Pentadecanoic Acid (C15:0 / Fatty15)

Side-by-side comparison of mechanisms, dosing, interactions, and stacking potential.

Black Seed Oil (Nigella sativa)Pentadecanoic Acid (C15:0 / Fatty15)
CategorySupplementsSupplements
Standard Dose
Timing
Cycle Duration
Evidence LevelModerateEmerging

Mechanism

Contains thymoquinone as active compound. Anti-inflammatory via NF-kB inhibition, immunomodulatory, hepatoprotective. Improves blood sugar regulation via AMPK activation. Supports respiratory health and has antimicrobial properties.

Contraindications

  • Pregnancy (uterotonic)
  • Pre-surgery (bleeding risk)

Mechanism

Odd-chain saturated fatty acid identified as essential. Strengthens cell membranes by integrating into phospholipid bilayer, activates AMPK and PPAR-alpha/delta, and inhibits mTOR. Repairs mitochondrial function. Epidemiologically associated with reduced cardiometabolic disease.

Contraindications

  • None established

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