Phosphatidylserine (PS) vs Wobenzym (Systemic Enzyme Complex)

Side-by-side comparison of mechanisms, dosing, interactions, and stacking potential.

Phosphatidylserine (PS)Wobenzym (Systemic Enzyme Complex)
CategorySupplementsSupplements
Standard Dose
Timing
Cycle Duration
Evidence LevelModerate-StrongModerate

Mechanism

Phospholipid concentrated in brain cell membranes. Supports neurotransmitter production (acetylcholine, dopamine), cortisol regulation, and membrane fluidity. Improves cognitive function, reduces exercise-induced cortisol, and supports HPA axis recovery.

Contraindications

  • Soy allergy (if soy-derived — use sunflower-derived instead)

Mechanism

Combination of bromelain, papain, trypsin, chymotrypsin, and pancreatin. Systemic enzyme therapy that degrades circulating immune complexes, reduces fibrin deposition, modulates cytokines (IL-6, TNF-alpha), and supports recovery from injury, surgery, and chronic inflammation.

Contraindications

  • Bleeding disorders
  • Pre-surgery
  • Severe liver or kidney disease

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