Pentadecanoic Acid (C15:0 / Fatty15) vs Phosphatidylserine (PS)

Side-by-side comparison of mechanisms, dosing, interactions, and stacking potential.

Pentadecanoic Acid (C15:0 / Fatty15)Phosphatidylserine (PS)
CategorySupplementsSupplements
Standard Dose
Timing
Cycle Duration
Evidence LevelEmergingModerate-Strong

Mechanism

Odd-chain saturated fatty acid identified as essential. Strengthens cell membranes by integrating into phospholipid bilayer, activates AMPK and PPAR-alpha/delta, and inhibits mTOR. Repairs mitochondrial function. Epidemiologically associated with reduced cardiometabolic disease.

Contraindications

  • None established

Mechanism

Phospholipid concentrated in brain cell membranes. Supports neurotransmitter production (acetylcholine, dopamine), cortisol regulation, and membrane fluidity. Improves cognitive function, reduces exercise-induced cortisol, and supports HPA axis recovery.

Contraindications

  • Soy allergy (if soy-derived — use sunflower-derived instead)

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