Micronized Progesterone vs Prasterone (DHEA)

Side-by-side comparison of mechanisms, dosing, interactions, and stacking potential.

Micronized ProgesteronePrasterone (DHEA)
CategoryHormonesHormones
Standard Dose
Timing
Cycle Duration
Evidence LevelStrongModerate

Mechanism

Bioidentical progesterone used to support luteal balance, sleep architecture, and selected HRT protocols.

Contraindications

  • Hormone-sensitive conditions without specialist oversight

Mechanism

Adrenal steroid precursor that can increase downstream androgenic and estrogenic metabolites depending on individual enzyme activity.

Contraindications

  • Hormone-sensitive cancers
  • Use only with lab follow-up

Not sure which is right for you?

Take our free assessment to get personalized recommendations based on your health goals, current stack, and biomarkers.

Get Your Free Protocol →or take the assessment →