Human Chorionic Gonadotropin (hCG) vs Prasterone (DHEA)

Side-by-side comparison of mechanisms, dosing, interactions, and stacking potential.

Human Chorionic Gonadotropin (hCG)Prasterone (DHEA)
CategoryHormonesHormones
Standard Dose
Timing
Cycle Duration
Evidence LevelStrongModerate

Mechanism

LH receptor agonist that stimulates intratesticular testosterone production and can help preserve fertility signaling in selected male hormone protocols.

Contraindications

  • Use only with endocrine supervision

Mechanism

Adrenal steroid precursor that can increase downstream androgenic and estrogenic metabolites depending on individual enzyme activity.

Contraindications

  • Hormone-sensitive cancers
  • Use only with lab follow-up

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